Basic Pharmacology Quiz – Part 4

1. Metabolic transformation (phase 1) is

2. Biotransformation of a medicinal substance results in:

3. Conjugation is :

4. Which of the following processes proceeds in the second phase of biotransformation?

5. Conjugation of a drug includes the following EXCEPT:

6. In case of liver disorders accompanied by a decline in microsomal enzyme activity the duration of action of some drugs is:

7. Half life (t ½) is the time required to:

8. Metabolic transformation and conjugation usually results in an increase of a substance biological activity:

9. Half life (t ½) doesn’t depend on:

10. Elimination is expressed as follows:

11. Elimination rate constant (Kelim) is defined by the following parameter:

12. The most rapid eliminated drugs are those with high glomerular filtration rate and actively secreted but aren’t passively reabsorbed:

13. Systemic clearance (CLs) is related with: